Search results for " cardiac function"

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Antihypertensive efficacy and effects of nitrendipine on cardiac and renal hemodynamics in mild to moderate hypertensive patients: Randomized control…

1992

In this study antihypertensive efficacy, safety, and the effects of short-term nitrendipine administration on central and renal hemodynamics were evaluated in mild to moderate hypertensives. Our final goal was to ascertain whether the reduction in blood pressure induced by nitrendipine treatment was associated with maintained renal function. After a run-in period with placebo, 26 hypertensives without cardiac or renal disease were randomly assigned to a double-blind 8-week controlled trial with nitrendipine (N) 20 mg once a day (13 pts) or hydrochlorothiazide (HCT) 25 mg once a day (13 pts). Renal hemodynamic measurements included effective renal plasma flow (ERPF) and glomerular filtration…

AdultMalemedicine.medical_specialtySettore MED/09 - Medicina InternaHemodynamicsRenal functionKidneyHydrochlorothiazideDouble-Blind MethodNitrendipineInternal medicinemedicineHumansPharmacology (medical)PharmacologyEjection fractionbusiness.industryNitrendipineHemodynamicsGeneral MedicineEffective renal plasma flowMiddle AgedSettore MED/11 - Malattie Dell'Apparato CardiovascolareFiltration fractionHydrochlorothiazideEndocrinologyRenal blood flowHypertensionSettore BIO/14 - FarmacologiaCardiologyFemaleCalcium channel blockers nitrendipine essential arterial hypertension cardiac function renal function.Cardiology and Cardiovascular Medicinebusinessmedicine.drugCardiovascular Drugs and Therapy
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Genistein supplementation and cardiac function in postmenopausal women with metabolic syndrome: Results from a pilot strain-echo study

2017

Genistein, a soy-derived isoflavone, may improve cardiovascular risk profile in postmenopausal women with metabolic syndrome (MetS), but few literature data on its cardiac effects in humans are available. The aim of this sub-study of a randomized double-blind case-control study was to analyze the effect on cardiac function of one-year genistein dietary supplementation in 22 post-menopausal patients with MetS. Participants received 54 mg/day of genistein (n = 11) or placebo (n = 11) in combination with a Mediterranean-style diet and regular exercise. Left ventricular (LV) systolic function was assessed as the primary endpoint, according to conventional and strain-echocardiography measurement…

Cardiac function curvemedicine.medical_specialtycardiac function; echocardiography; genistein; menopause; metabolic syndromegenistein; metabolic syndrome; menopause; cardiac function; echocardiographyGenisteinlcsh:TX341-641030204 cardiovascular system & hematologyPlaceboArticle03 medical and health scienceschemistry.chemical_compound0302 clinical medicineDouble-Blind MethodInterquartile rangeInternal medicinemedicineHumans030212 general & internal medicineEnd-systolic volumeBody surface areaNutrition and DieteticsEjection fractionbusiness.industryCardiac functionHeartMiddle Agedmedicine.diseaseGenisteinMetabolic syndromePostmenopauseEndocrinologychemistryEchocardiographyDietary SupplementsCardiologyCardiac function; Echocardiography; Genistein; Menopause; Metabolic syndrome; Food ScienceFemaleMetabolic syndromeMenopausebusinesslcsh:Nutrition. Foods and food supplyFood Science
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Acute impact of an endurance race on cardiac function and biomarkers of myocardial injury in triathletes with and without myocardial fibrosis.

2019

Aims The aim of this study was to investigate the occurrence of myocardial injury and cardiac dysfunction after an endurance race by biomarkers and cardiac magnetic resonance in triathletes with and without myocardial fibrosis. Methods and results Thirty asymptomatic male triathletes (45 ± 10 years) with over 10 training hours per week and 55 ± 8 ml/kg per minute maximal oxygen uptake during exercise testing were studied before (baseline) and 2.4 ± 1.1 hours post-race. Baseline cardiac magnetic resonance included cine, T1/T2, late gadolinium enhancement (LGE) and extracellular volume imaging. Post-race non-contrast cardiac magnetic resonance included cine and T1/T2 mapping. Non-ischaemic my…

MaleTime FactorsEpidemiologyBlood Pressure030204 cardiovascular system & hematologyFull Research PaperVentricular Function LeftRunning0302 clinical medicineSports CardiologyCreatine Kinase MB FormAthlete's heartpost-race myocardial oedemaEdema CardiacEjection fractionTroponin TMiddle Agedddc:late gadolinium enhancementpost-race cardiac functionHypertensionCardiologyCardiology and Cardiovascular MedicineCardiomyopathiesCardiac function curveAdultmedicine.medical_specialtyAdolescentMagnetic Resonance Imaging Cinecardiac magnetic resonanceCardiac dysfunction03 medical and health sciencesYoung AdultLinear gingival erythemaTroponin TPredictive Value of TestsInternal medicinemedicineHumanscardiovascular diseasesExerciseSwimmingbusiness.industryMyocardiumT2 and T1 mapping030229 sport sciencesmedicine.diseaseFibrosisBicyclingBlood pressureAthletesCase-Control StudiesPhysical EnduranceVentricular Function RightMyocardial fibrosismyocardial fibrosisbusinessCardiac magnetic resonanceBiomarkersEuropean journal of preventive cardiology
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